Do not take Tadala-Denk

• if you are allergic to Tadalafil or any of the other ingredients of this medicine.
• if you are taking any form of organic nitrate or nitric oxide donors such as amyl nitrite. This is a group of medicines (“nitrates”) used in the treatment of angina pectoris (“chest pain”). Tadalafil has been shown to increase the effects of these medicines. If you are taking any form of nitrate or are unsure, tell your doctor.
• if you have serious heart disease or recently had a heart attack within the last 90 days.
• if you recently had a stroke within the last 6 months.
• if you have low blood pressure or uncontrolled high blood pressure.
• if you are taking riociguat. This drug is used to treat pulmonary arterial hypertension (i.e. high blood pressure in the lungs) and chronic thromboembolic pulmonary hypertension (i.e. high blood pressure in the lungs secondary to blood clots). PDE5 inhibitors, such as Tadalafil, have been shown to increase the hypotensive effects of this medicine. If you are taking riociguat or are unsure, tell your doctor.
• if you ever had loss of vision because of non-arteritic anterior ischemic optic neuropathy (NAION), a condition described as “stroke of the eye”.

 
Warnings and precautions:

Talk to your doctor or pharmacist before taking Tadala-Denk:
Be aware that sexual activity carries a possible risk to patients with heart disease because it puts an extra strain on your heart.
If you have a heart problem you should tell your doctor.

 
Before taking the tablets, tell your doctor if you have:

• sickle cell anemia (an abnormality of red blood cells).
• multiple myeloma (cancer of the bone marrow).
• leukemia (cancer of the blood cells).
• any deformation of your penis.
• a serious liver problem.
• a severe kidney problem.

 
Other medicines and Tadala-Denk:

Some medicines may be affected by Tadala-Denk or they may affect how well Tadala-Denk will have an effect. Do not take Tadala-Denk if you are already taking nitrates.

 
Tell your doctor or pharmacist if you are already taking

• medicines such as ketoconazole tablets (to treat fungal infections) and protease inhibitors for treatment of AIDS or HIV infection.
• an alpha blocker (used to treat high blood pressure or urinary symptoms associated with benign prostatic hyperplasia).
• other medicines to treat high blood pressure.
• riociguat.
• a 5-alpha reductase inhibitor (used to treat benign prostatic hyperplasia).
• phenobarbital, phenytoin and carbamazepine (anticonvulsant medicines).
• rifampicin, erythromycin, clarithromycin or itraconazole.
• other treatments for Erectile Dysfunction.